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As Above, So Below - Part Four


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"During courtship," I noted, "two individuals should be taking a look at the degree of conformational compatibility of the entire range of their respective packages of primary and tertiary structures involving their preference hierarchies.

Usually, however, many people get caught up with just a few points of attraction, such as, say, sexuality and family, while overlooking much of the rest of the dynamics of the way two preference hierarchy sequences operate, not only within themselves, but in relation to the other person's primary and tertiary structures, as well.

"Even if we were to limit attention to just the small set of themes that form the primary sites of relational activity of two people's folded preference sequences, most people don't look at the dynamics of the situation very closely. I'll give an example of what I mean here.

"Let's assume that person 'A' has a primary activity site consisting of themes such as family, security, sexuality, commitment and spirituality. Let's further assume that person 'B' has a primary activity site consisting of independence, sexuality, commitment, security and family.

"On the surface, there would seem to be quite a bit of compatibility between these two people. Four out of five of the indicated themes match- namely, family, security, sexuality and commitment."

"In reality, however, there may be very different kinds of dynamics and interpretive processes going on within each person in relation to the themes which form their respective active relational sites. To begin with, we don't know the precise sequence of the preference hierarchy rankings for either of these people.

"In addition, we don't know how the attractive and repulsive tendencies in their different preference orderings cause the respective sequences to fold in order to form the active sites in question. Moreover, we don't even know what each of the people means by the themes that are thought to be held in common.

"Each of the two, for example, has the themes of sexuality and family as part of their active site. But, do they necessarily value them or think about them in the same way?

"For one person, sexuality may be a means to having a family. For the other person, family may be considered to be an incidental outcome of sexuality.

"One individual may look at family purely in terms of the notion of a nuclear family and considers the notion of an extended family to be both intrusive as well as problem-laden. The other person may believe that an extended family enriches and supports the nuclear family and is, therefore, something which is very fundamental and necessary.

"One person may look for security through relationships. The other individual may feel security is rooted in money and property.

"Person 'A' believes commitment is something the other person needs to provide. Person 'B' feels the same way.

"The independence of person 'B' and the spirituality of person 'A' may or may not find a way to coexist. A lot depends on the kind of independence and spirituality one is talking about, and a lot depends on how independence and spirituality fit into their respective preference sequences.

"Presumably, of course there would be very few, if any, instances in which the primary and tertiary structures of both individuals would be perfectly compatible. Consequently, the problem is one of trying to assess the relative degrees of compatibility and incompatibility that are present.

"To complicate matters, the preference hierarchy sequences of many people often do not remain the same over the course of a lifetime. Sometimes these alterations are relatively minor, and sometimes the transformations in the hierarchy are considerable.

"When one looks at the incredible complexity of the problems involved in matching up the primary and tertiary structures of two people, one is struck by a number of considerations. Firstly, one should not be surprised by the high incidence of divorce, separation and general unhappiness in most marriages. Secondly, one should be surprised by the existence of relationships which are characterized by any degree of long-term stability, happiness and fulfilment.

"Thirdly, in light of all the domestic and social problems that arise out of couples with non-matching preference hierarchies, one can't help but be surprised that so few, if any, of our primary and secondary schools devote time to helping students learn about the ways in which the ranking, interpreting and dynamics of the twenty-plus themes mentioned earlier has both short-term and long-term consequences for the health and success of one's relationships with other people."

Jennifer said: "At the risk of inviting the wrath of the powers that be, I'm still waiting for some kind of clarification on the significance of secondary structure in both proteins as well as preference hierarchies. If you delay much more in providing an explanation for what you claim is a matter of family values, I'm going to begin to suspect you're really a politician running for office who's trying to dodge the tough issues."

"Those are potentially slanderous sentiments, young lady, especially the politician angle," I charged. "I find them most offensive and foul.

"However," I offered, in a more conciliatory tone, "since you have, once again, persisted in raising this matter, I feel the time has come for me speak on this matter of secondary structure. I'm sure, after hearing my explanation, you will see I have been neither hiding nor dodging anything. Hopefully, these vicious innuendoes concerning my integrity will be laid to rest once and for all."

Sniffing away the last of my pseudo-indignation, I said: "Although there are exceptions to the rule, nonetheless, the conformational shapes of the vast majority of proteins fall into two broad categories of classification. One category of proteins is known as fibrous, and the other conformational type is referred to as globular.

"Globular proteins are relatively tightly coiled structures, assuming, as their name indicates, a globular or spherical form. Most of the, roughly, two thousand enzymes about which biologists know are examples of globular proteins. In addition, there are a number of proteins with transport or hormonal functions, that also are globular in nature. Furthermore, all of the antibodies fall under the globular category of proteins.

"Much, but not all, of the protein theory of relationships is built around the properties and qualities of globular proteins. Nonetheless, there still is room in the theory to accommodate some of the characteristics of fibrous proteins as well.

"Generally speaking, fibrous proteins are made up of chains of polypeptides that run in parallel with one another along a given axis. This category of protein constitutes the essential material that forms, among other things, connective tissue in more complex animals. Such fibrous proteins are found in bones, tendons and elastic connective tissue.

"The, now infamous, secondary structure of proteins refers to the repetitive arrangement of polypeptides that extends longitudinally along one dimension. The backbone of these kinds of polypeptide chain often are either helically coiled or run in a zig-zag fashion down the length of the chain.

"Sometimes, a number of individual helical coils wind themselves around one another in the same manner in which strands of hemp are intertwined to form a length of rope. This is referred to as supercoiling.

"If we substitute, once again, the notion of a preference hierarchy sequence for a polypeptide chain, then one has little difficulty in applying the idea of secondary structure to human relations. For example, the recurring arrangement of polypeptide chains that is characteristic of secondary structure can be likened to the members of a family.

"Taken collectively, relationships among the members of the family constitute the connective tissue that binds the family together. This is especially clear in the case of supercoiled helical structures whose individual strands or 'lives' become intertwined over time.

"Just as the functional effectiveness of a given kind of connective tissue will depend on both the quality of its individual polypeptide chains as well as on the way these chains of polypeptides interact with one another, so, too, is this the case with respect to the character and dynamics of the preference hierarchy sequences of the members of a family. In both polypeptide chains and preference sequences, defective features in either of the foregoing two aspects of the secondary structure of connective tissue could lead to problematic functioning in such tissue.

"Dysfunctional families arise out of the way the preference hierarchies of the individual members of the family play off against, and affect, one another. Any one, or combination, of the twenty-plus themes I mentioned earlier could be the source of difficulties in a family. Differences among family members in ranking hierarchies, or differences of interpretation concerning the meaning and significance of many themes, or pathological dynamics involving the interaction of the preference hierarchies of family members, can all contribute to the manner in which a family is dysfunctional."



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