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The Science of Presumption Can Be A Beautiful Thing - Part 4


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"Actually, Dr. Yardley," Mr. Tappin responded, "I'm asking neither kind of question. The question which I'm posing is more like the following: given that legitimate questions can be raised about the availability of polyamines such as spermadine in the Archean era, does the fact a ribozyme can be experimentally induced to overcome its inherent sequence specificity under artificial, and prebiotically unrealistic, conditions, really bring us any closer to answering the question of how life came into being, especially in view of the very strong possibility that ribozymes might not have been capable of being synthesized in the prebiotic world?

"In other words, Professor, many evolutionary researchers seem to be saying: if such and such a set of conditions holds, then such and such a outcome is possible, and if we assume that these conditions did hold during the Archean era, then this constitutes evidence in support of evolutionary theory. Yet, the question which really needs to be asked, and answered, is this: do we have any plausible means of demonstrating the likelihood that such a set of conditions existed and that such an outcome did, in fact, take place during the Archean era?"

"All of evolutionary theory," Dr. Yardley asserted, "is about establishing and demonstrating that some conditions, events, processes and outcomes may have been more likely than other conditions, events, processes and outcomes."

"That may well be true, Professor, but there seems to be a heavy fog warning which is being posted with respect to conceptual travel in the areas of 'demonstration' and 'likelihood'," the defense counsel replied. "For instance, you previously said the spermadine experiment can be considered to constitute evidence in support of evolutionary theory because, irrespective of whether it is right or wrong, the findings of the experiment can be used to help shape and modulate that theory, and, yet, at the same time, the spermadine experiment may have nothing to do with the Archean era, and, therefore, by implication, the spermadine experiment may have nothing to do with one of the most important questions facing evolutionary theory - namely, how did life come into being.

"In effect, I'm having a little trouble, Dr. Yardley, understanding how you propose to reconcile these seemingly antagonistic elements. If, and the viability of this 'if' needs to be examined ... if one can raise questions which cast serious doubt on the degree of relevance of the spermadine experiment with respect to helping us resolve the origin-of-life issue, then how does it serve as evidence for evolutionary theory?"

"Science," suggested the professor, "is about empirically and conceptually exploring possibilities concerning the physical/material world in a methodical, rigorous fashion. Within certain limits, whatever an experiment permits us to eliminate in the way of possibility, we eliminate. Similarly, within certain limits, whatever an experiment permits us to retain in the way of possibility, we retain.

"Over time, the relationship between what has been eliminated and what is retained takes on a structural form. We describe this relationship through the concrete vocabulary of hypothesis, conjecture, experiment, methodology, data, evidence, analysis, principles, laws, theory, and model.

"Unfortunately, at any given time, there is often a certain amount of ambiguity which surrounds the issue of what justifiably can be eliminated or retained as a function of the empirical data and experimental results which may be in our possession. The spermadine experiment gives expression to a certain amount of this sort of ambiguity.

"On the one hand, as you rightly point out," affirmed the professor, "we don't know whether spermadine, or ribozymes for that matter, existed during the Archean era, although there is evidence which can be offered both for and against such possibilities. Even if we eliminate the ontological possibilities of spermadine and ribozymes from the picture, we still can retain the idea that something like them may have existed and which, if they did, would help resolve certain kinds of problem, so we proceed to try to determine whether we should eliminate or retain such conceptual possibilities on the basis of forthcoming empirical data and conceptual reflection.

"On the other hand, if spermadine and ribozymes did exist during the Archean era - a possibility concerning which, once again, evidence can be offered both for and against - then the spermadine experiment is revealing a very interesting possibility that ought to be retained and explored further. Now, although the available evidence does suggest there are a variety of factors which mitigate against continuing to retain either spermadine or ribozymes as viable, plausible pieces of the origin-of-life puzzle, in my opinion, we have not yet reached a point where these possibilities can justifiably be eliminated from the picture.

"Quite frequently, there is a constant dialectic and tug-of-war going on between how we feel about what, both conceptually and empirically, should be eliminated and what should be retained at any given time. Consequently, despite the fact something may have a theoretical status, vis-a-vis elimination and retention, which is ambiguous, nonetheless, that ambiguous element still can come to have a shaping influence on one's theories, models, conjectures and hypotheses, even while there are other factors which serve as counter-indications to this shaping influence."

"What happens," hypothesized the lawyer, "if your feelings about the proper relationship between what is to be eliminated and what is to be retained is at odds with my feelings about the proper relationship between what is to be eliminated and what is to be eliminated?"

"Then," the professor said with a shrug of this shoulders, "we have a difference of opinion."

"Is there any way to resolve such a difference of opinion," the defense counsel asked.

"Yes and no," answered the professor. "One can try to do more science until the balance of evidence seems to point more in the direction of one kind of relationship of elimination/retention rather than some other such relationship. However, this often is easier said than done, and, moreover, there often are other ideas about the proper relationship between what should be eliminated and retained which arise in the meantime and complicate any straightforward resolution of the original difference of opinion.

"Progress does occur in the sense that despite a variety of differences of opinion about numerous issues concerning what should be retained and what should be eliminated, a broad consensus develops about some of the things, both empirical and conceptual, which should be eliminated and some of the things which should be retained. Even here, however, one finds some people who are resistant to either eliminating possibilities or retaining possibilities despite the presence of a general consensus among many researchers on such matters."

"Does the existence of a consensus," queried the lawyer," necessarily mean this decision on what, in broad terms, should be eliminated or retained is, in some sense, a correct one?"

"Not at all," Dr. Yardley stated. "Yet, one could say that where such consensus exists, there usually is considerable justification which can be offered through empirical observations, experimental results and conceptual analysis, in support of such decisions, and, therefore, anyone who wishes to oppose such decisions will be swimming against the tide of an informed consensus of opinion.

"Of course, historically, conceptual revolutions often have come in the form of one or more people who believed the wrong consensus-decisions had been made about the possibilities which are being eliminated, retained or even entertained. Apparently, your client Mr. Corrigan is an individual who feels consensus opinion concerning evolutionary theory is wrong-headed, but whether his opposition will result in a revolution or merely fall by the wayside as a very minor historical oddity will be decided, to some extent, by what the present jury and other, similar forums of public opinion, decide."



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